thumb thumb

Zinc Finger Folds and Functions | SpringerLink

Zinc fingers (ZnFs) are small (∼20–100-residue) domains that coordinate one or more zinc ions, usually through cysteine and histidine sidechains, to stabilize their fold. The term was first used to describe a repeated motif in a zinc-binding region of the Xenopus laevis transcription factor III (Miller et al. 1985 ) but has since been used ...

thumb thumb

Zinc finger protein 165 - WikiMili, The Free Encyclopedia

Zinc finger protein 165 is a protein that in humans is encoded by the ZNF165 gene. Zinc finger protein 165 is a protein that in humans is encoded by the ZNF165 gene. WikiMili The Free Encyclopedia. Zinc finger protein 165 Last updated March 01, 2019. ZNF165; Identifiers; Aliases: ZNF165, CT53, LD65, ZSCAN7, zinc finger protein 165:

thumb thumb

AN1 zinc finger - Wikipedia

In molecular biology, the AN1-type zinc finger domain, which has a dimetal (zinc)-bound alpha/beta fold.This domain was first identified as a zinc finger at the C terminus of AN1 SWISSPROT, a ubiquitin-like protein in Xenopus laevis. The AN1-type zinc finger contains six conserved cysteines and two histidines that could potentially coordinate 2 zinc atoms.

thumb thumb

Zinc-finger | Article about Zinc-finger by The Free Dictionary

Myocardial ischemic preconditioning upregulated protein 1(Mipu1):zinc finger protein 667--a multifunctional KRAB/[C.sub.2][H.sub.2] zinc finger protein The CCCH tandem zinc-finger protein zfp36l2 is crucial for fertility and early embryonic development.

thumb thumb

ZMAT5 - Zinc finger matrin-type protein 5 - Homo sapiens ...

Zinc finger i: 51 – 79: C3H1-type PROSITE-ProRule annotation. Add BLAST: 29: Keywords - Domain i Zinc-finger Phylogenomic databases. eggNOG i: KOG3454 Eukaryota COG5136 LUCA GeneTree i: ENSGT00390000009869: HOGENOM i: CLU_100385_1_0_1: InParanoid i: Q9UDW3: KO i: K13152: OMA i: FQYPPGW: OrthoDB i: 1541869at2759: PhylomeDB i: Q9UDW3 ...

thumb thumb

C2H2 zinc finger proteins greatly expand the human ...

Feb 18, 2015· Cys2-His2 zinc finger (C2H2-ZF) proteins represent the largest class of putative human transcription factors. However, for most C2H2-ZF proteins it …

thumb thumb

Zinc finger - WikiMili, The Free Encyclopedia

Zinc finger Last updated August 12, 2019 Cartoon representation of the Cys2His2 zinc finger motif, consisting of an α helix and an antiparallel β sheet.The zinc ion (green) is coordinated by two histidine residues and two cysteine residues. Cartoon representation of the protein Zif268 (blue) containing three zinc fingers in complex with DNA (orange). The coordinating amino acid residues and ...

thumb thumb

Zinc finger, DHHC-type containing 13 | definition of zinc ...

A gene on chromosome 11p15.1 that encodes a DHHC-type zinc finger protein and palmitoyltransferase which palmitoylates HD and GAD2 and mediates Mg2+ transport. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the webmaster's page for free fun content .

thumb thumb

Zinc finger | Article about zinc finger by The Free Dictionary

The global genome engineering market or genome editing market segmentation is based on technologies (clustered regularly interspaced short palindromic repeats, transcription activator-like effector nuclease, zinc finger nuclease), applications (animal genome engineering, cell line engineering, plant genome engineering), end users (academics, clinical research organizations, pharmaceutical and ...

thumb thumb

Zinc finger Facts for Kids - Kids encyclopedia facts

May 22, 2020· Zinc finger nucleases (or ZFN) are a tool used to target genes and change DNA.It is one of three methods of changing the genome with engineered nucleases.. They have two parts. Zinc fingers are man-made molecules made of a protein and zinc.Each binds to a specific DNA. Zinc-finger nucleases (ZFNs) are enzymes got by fusing a zinc finger to a DNA cleavage enzyme called a Fokl.

thumb thumb

Zinc finger protein 444 - Wikipedia

Zinc finger protein 444 is a protein that in humans is encoded by the ZNF444 gene. Function. This gene encodes a zinc finger protein which activates transcription of a scavenger receptor gene involved in the degradation of acetylated low-density lipoprotein (Ac-LDL) (Adachi H, Tsujimoto M (2002).

thumb thumb

Zinc | Encyclopedia.com

Zinc-dependent enzymes can be found in all known classes of enzymes. Structural role: Zinc also maintains the structure of proteins and cell membranes. A finger-like structure, called a zinc finger motif, strengthens the structure of several important proteins and enzymes. For instance, that of the antioxidant copper-zinc superoxide dismutase ...

thumb thumb

Zinc Finger | SpringerLink

The C 2 H 2 zinc finger domain, which can insert its α ‐helix into the major groove of DNA, is one of the most common DNA‐binding motifs in eukaryotic transcription factors. A second type of zinc finger structure, designated the C 4 zinc finger, is found in nuclear receptors.

thumb thumb

Zinc finger dna binding domain | Article about Zinc finger ...

Looking for Zinc finger dna binding domain? Find out information about Zinc finger dna binding domain. A small structural domain that is organized around a zinc ion and is found in many gene-regulatory proteins Explanation of Zinc finger dna binding domain

thumb thumb

Zinc-finger | Article about Zinc-finger by The Free Dictionary

Their topics include emerging trends of Z20/AN1 zinc-finger proteins in improving rice productivity under abiotic stress, technological developments for abiotic stress in rice, the assessment of aromatic content and in-vitro responses in traditional Indian rice varieties, agrobacterium-mediated genetic transformation practices for improving rice quality and production, and the role of genetic ...

thumb thumb

Zinc fingers | Article about Zinc fingers by The Free ...

Among the metalloproteins and metal-binding domains, the zinc finger motif, characterized by the presence of a structural zinc ion, is surely the most emblematic [12-15] as it has been intensively studied for its known ubiquitous presence in the biological world (e.g., 3% of the genes of the human genome encode for zinc fingers containing ...

thumb thumb

Zinc finger nuclease - Wikipedia

Zinc finger From Wikipedia, the free encyclopedia Jump to navigation Jump to search ...

thumb thumb

Zinc Finger Transcription Factor - an overview ...

Maryam Ghaedi, Fumio Takei, in Encyclopedia of Immunobiology, 2016. Bcl11b. The zinc-finger transcription factor Bcl11b, which is expressed in T cells from the double-negative 2 (DN2) stage of development, is required for the development of αβ T cells (Wakabayashi et al., 2003).All ILC2s and a subset of CHILPs express Bcl11b, and Bcl11b + CHILPs develop into ILC2s upon transplantation (Yu …

thumb thumb

Zinc finger protein | Article about Zinc finger protein by ...

Zn, a chemical element of Group II of Mendeleev's periodic system. Atomic number, 30; atomic weight, 65.38. A bluish white metal, zinc occurs in the form of five stable isotopes, with mass numbers 64, …

thumb thumb

ZNHIT1 - Zinc finger HIT domain-containing protein 1 ...

Zinc finger HIT domain-containing protein 1. Alternative name(s): Cyclin-G1-binding protein 1. Zinc finger protein subfamily 4A member 1. p18 Hamlet Gene names i: Name:ZNHIT1. Synonyms: CGBP1, ZNFN4A1. Organism i: Homo sapiens (Human) Taxonomic identifier i: 9606 : Taxonomic lineage i › Eukaryota › › Metazoa › › › › Chordata ...

thumb thumb

Zinc finger nuclease - WikiMili, The Free Encyclopedia

A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn 2+) in order to stabilize the fold.Originally coined to describe the finger-like appearance of a hypothesized structure from Xenopus laevis transcription factor IIIA, the zinc finger name has now come to encompass a wide variety of differing protein structures.

thumb thumb

Zinc finger - Simple English Wikipedia, the free encyclopedia

Zinc finger nucleases (or ZFN) are a tool used to target genes and change DNA.It is one of three methods of changing the genome with engineered nucleases.. They have two parts. Zinc fingers are man-made molecules made of a protein and zinc.Each binds to a specific DNA. Zinc-finger nucleases (ZFNs) are enzymes got by fusing a zinc finger to a DNA cleavage enzyme called a Fokl.

thumb thumb

* Zinc finger (Biology) - Definition,meaning - Online ...

Zinc Fingers in Biological Systems Disclaimer: This essay has been submitted by a student. This is not an example of the work written by our professional essay writers. You can view samples of our professional work here. [] zinc finger (metal-binding finger) A motif of which seven or more may appear in a DNA-binding protein.

thumb thumb

Zinc finger - Blogger

Zinc finger From Wikipedia, the free encyclopedia Jump to navigation Jump to search ...

thumb thumb

Zinc Finger Protein - an overview | ScienceDirect Topics

M. Isalan, in Encyclopedia of Biological Chemistry (Second Edition), 2013. Evolution. Zinc fingers may have evolved originally from peptides, which maintained a simple ββα structure (similar to that shown in Figure 1(b)) independently of zinc.In any case, the ββα fold is one of the smallest possible units of protein tertiary structure, and may therefore be one of the oldest.

thumb thumb

Zinc_finger

Classes. One very well explored sub-set of zinc-fingers (the C 2 H 2 class) comprises a pair of cysteine residues in the beta sheets and two histidine residues in the alpha helix which are responsible for binding a zinc ion. The two other classes of zinc finger proteins are the C 4 and C 6 classes. Zinc fingers are important in regulation because when interacted with DNA and zinc ion, they ...